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A REVOLUTION IN CANCER MEDICINE

Immunotherapies

Today’s health challenges demand 21st century solutions. As one of the world’s leading clinics for immunotherapy, the Hallwang Clinic offers targeted and patient-centered treatment strategies.

Zwei Mitarbeiter der Hallwang Clinic sprechen mit einer Patientin im Rollstuhl.

At the Hallwang Private Oncology Clinic, we are proud to be among the world’s leading facilities for personalized cancer treatments. Our specialty lies in cutting-edge immunotherapies. Unrestricted access to the most advanced cancer treatments of our time sets us apart as one of the best cancer treatment centers worldwide.

Targeted, Patient-Centered Care for the 21st Century

As cancer treatments continue to evolve, traditional approaches alone are no longer sufficient. Modern cancer treatments demand targeted, patient-centered strategies that go beyond conventional methods such as surgery, chemotherapy, and radiotherapy. At our clinic, we focus on developing individualized treatment plans for every patient to ensure the most effective therapy is utilized for their specific condition.

A Holistic Approach to Cancer Treatment

At the Hallwang Clinic, we are well-versed in the three conventional approaches to cancer treatment:

  • Surgery: Some tumors can be surgically removed if they are localized (non-metastatic).
  • Chemotherapy: Often administered before, after, or as an alternative to surgery.
  • Radiotherapy: Frequently combined with surgery or chemotherapy to achieve optimal outcomes.

However, we recognize that chemotherapy and radiotherapy can cause significant cytotoxic side effects. Therefore, we place a strong emphasis on advanced immunotherapy – a groundbreaking treatment that offers our patients a promising perspective.

Immunotherapy: Unlocking the Body’s Potential to Fight Cancer

Immunotherapy is one of the most significant advancements in cancer treatment. By enhancing the immune system, it enables the recognition and destruction of cancer cells. Our goal is to provide our patients with unlimited access to the most advanced immunotherapeutic solutions, offering them the most sophisticated options available for their treatment.

Our approach to immunotherapy encompasses both active and passive immunization:

  • Active Immunization: This approach trains the patient’s immune system to recognize and attack tumor cells, leading to cell destruction or slowed tumor growth.
  • Passive Immunization: We administer antibodies or antibody fragments that specifically target and destroy cancer cells.

With this integrative approach, we aim to maximize the individual treatment success of each patient.

Immunotherapeutic approaches

Antibody-drug conjugates – ADCs

Antibody-drug conjugates or ADCs are an important class of highly potent biopharmaceutical drugs designed as a targeted therapy for cancer treatments. Unlike chemotherapy, ADCs are intended to target and kill only cancer cells and spare healthy cells. ADCs are complex molecules composed of an antibody linked to a biologically active cytotoxic (anticancer) drug.

Checkpoint-antibodies / Checkpoint block – Anti-CTLA-4 & Anti-PD-1/L-1

The development of checkpoint-blocking antibodies, such as those directed against cytoxic T-lymphocyte antigen 4 (CTLA-4) and programmes death 1 receptor /PD-1/L-1), has shown to be one of the most promising approaches to activating therapeutic antitumor immunity in the treatment of an expanding list of malignancies.
Immune checkpoints refer to a wide range of inhibitory pathways that are crucial for maintain self-tolerance and modulation of immune responses in order to minimize tissue damage. But it is now known that tumors modify certain immune-checkpoint pathways as a major mechanism of immune resistance, particularly against T cells that are specific for recognition and targeting of tumor antigens.
Many of these regulatory immune checkpoints can now be blocked by antibodies or modulated by recombinant forms of ligands and receptors. Checkpoint blocking antibodies (anti-CTLA-4 or anti-PD-1/L-1), have shown great success already in clinical studies. By blocking CTLA-4 and PD-1, these checkpoint antibodies enhance the function of T cells to fight cancer cells.

Monoclonal- / Polyclonal- /Trifunctional-Antibodies

Monoclonal-antibodies are active proteins which are directed against a single epitope. A physiologically (naturally) occurring immune response against an antigen that infiltrated into the body, is polyclonal and directed against different epitopes. A trifunctional antibody is a monoclonal antibody with binding sites for two different antigens, typically CD3 and a tumour antigen, making it a type of bispecific monoclonal antibody. In addition, its intact Fc-part can bind to an Fc receptor on accessory cells like conventional monospecific antibodies. Consequently, immune cells like T cells (via CD3) and monocytes/macrophages, nature killer cells, dendritic cells or other Fc receptor expressing cells are linked to the tumour cells, leading to their elimination.

Immune priming / Polyclonal- / Oligo- / IDO-Strategies & Oncolytic Viro-therapies

These strategies aim at inducing durable T-cell responses to tumour antigens, which are recognized by cytotoxic T lymphocytes, and belonging to the immunomodulating/educating therapies with multiple activities, i.e. including modulation of immune cell compartments, complement activation, suppression of various inflammatory mediators, including cytokines, and metalloproteinases, or effectively activates apoptosis and conquer immunosuppression.
Oncolytic virus therapy has recently been recognized as a promising new therapeutic approach for cancer treatment. An oncolytic virus is defined as a genetically engineered or naturally occurring virus that can selectively replicate in and kill cancer cells while sparing normal tissues. Oncolytic virus therapy uses the virus itself as an active drug reagent. Nowadays one also knows that some types of cancer are caused by viruses. Traditional vaccines against those viruses can prevent those types of cancer.

Personalized Immunotherapy: The Hallwang Advantage

What distinguishes the Hallwang Private Oncology Clinic is our ability to tailor immunotherapy treatments to the unique needs of every patient. With our world-class network of experts, close research collaborations, and access to the most innovative therapies, we hold a decisive advantage in delivering personalized cancer treatments.

Our commitment is to always stay ahead. Unlike other countries, the healthcare system in Germany allows us comprehensive therapy evaluation and unrestricted access to innovative treatments. This liberal and globally leading approach enables the Hallwang Clinic’s medical team to implement individualized therapy strategies beyond clinical trials – always in accordance with international guidelines and based on sound medical indications. Many of the off-label therapies applied at the Hallwang Clinic have since become integral parts of international guidelines.

The Role of Our Expert Network

Our clinic’s strong network of leading researchers, scientists, and oncologists enables us to continually refine and adapt our treatments based on the latest scientific discoveries. This unique collaboration ensures that we offer state-of-the-art, personalized immunotherapy precisely tailored to the genetic profile of each patient’s cancer. This unlimited access to groundbreaking therapies makes the difference in delivering superior outcomes and improving survival rates.

Why Choose the Hallwang Clinic

  • Unlimited Access to Immunotherapy: We provide the latest and most effective groundbreaking immunotherapies that target cancer cells with precision.
  • Global Recognition: As one of the world’s leading cancer centers, we are renowned for our expertise in immuno-oncology and personalized cancer treatment.
  • Personalized Treatment Plans: Every patient receives an individually tailored treatment strategy based on the latest research and their specific cancer profile.
  • Expert Network: Our clinic maintains a vital network of oncologists, researchers, and specialists worldwide, dedicated to advancing cancer treatment.
  • State-of-the-Art Facilities: We offer access to cutting-edge medical technologies and therapies, including the most advanced immunotherapeutic options.

Embrace the Most Advanced Cancer Treatment

At the Hallwang Private Oncology Clinic, our mission is not only to provide the best possible care today but also to actively shape the future of cancer treatment. With unlimited access to immunotherapy, a focus on personalized care, and an exceptional global network, we are uniquely positioned to offer world-class cancer treatment and improve patient outcomes.

If you are seeking innovative, highly effective, and integrative treatment methods, as well as the best cancer treatment center worldwide, the Hallwang Clinic is your unique destination.

We warmly invite you to contact us to learn more about our holistic cancer treatment center and your individualized treatment options at the Hallwang Clinic.

Important: Our oncological team is happy to talk to you by phone to get a deeper understanding about your specific case, enabling to provide you with a provisional treatment plan and cost estimate. Our oncologists will provide you all the details on medications, therapeutics and treatments including underlying mechanism and side effects. After a physical examination and an in-depth discussion with you on-site, the definite treatment plan will be discussed. Please understand that complex medical processes as mentioned above can only be explained through a thorough consultation on-site

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